circRNA basic information
circBase ID: hsa_circ_0129039
Name: hsa_circ_LIFR
Synonym: chr5: 38481299-38530666-
Host Gene: LIFR
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: Papillary thyroid carcinoma
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tissue; neighboring non-tumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: potential diagnostic biomarker for PTC
Molecular mechanism: not specified (only expression profiling and diagnostic evaluation)
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; ROC Analysis
Clinical significance:

shows potential diagnostic capabilities for diagnosing PTC
Description:

chr5: 38481299-38530666- (hsa_circ_0129039; host gene LIFR) is markedly down-regulated in papillary thyroid carcinoma and was among the RT-qPCR-verified circRNAs evaluated for diagnostic potential using ROC curves.
Confidence score:

0.4679
Other information
Title:

Expression Profiles of Circular RNAs in Human Papillary Thyroid Carcinoma Based on RNA Deep Sequencing.

Journal: OncoTargets and therapy
Published: 2021
PubMed ID: 34188490
Study type:

combined biological and clinical study
Data availability: GSE171011
Code availability: -