circRNA basic information
circBase ID: hsa_circ_0020396
Name: hsa_circ_DOCK1
Synonym: -
Host Gene: DOCK1
Genomic location(hg19): chr10:128768965-128908618:+
Genomic location(hg38): chr10:126970701-127110354:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid carcinoma
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tumor tissues; tumor-adjacent normal thyroid tissues; whole blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-103a-2-5p, hsa-miR-132-3p, hsa-miR-196a-5p, hsa-miR-138-2-3p, hsa-miR-136-5p
Biological function: unknown
Molecular mechanism: Predicted ceRNA mechanism via miRNA response elements (bioinformatics).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0020396 is down-regulated in papillary thyroid carcinoma and was validated in thyroid tissues and whole blood. The study reported predicted miRNA response elements but did not experimentally validate a specific functional mechanism for this circRNA.
Confidence score:

0.4032
Other information
Title:

Circular RNA profiling reveals a potential role of hsa_circ_IPCEF1 in papillary thyroid carcinoma.

Journal: Molecular medicine reports
Published: 2021
PubMed ID: 34165176
Study type:

combined biological and clinical study
Data availability: GSE173299
Code availability: -