circRNA basic information
circBase ID: hsa_circ_0001566
Name: hsa_circ_TEP1
Synonym: circ_0001566
Host Gene: TEP1
Genomic location(hg19): chr5:179688683-179707608:-
Genomic location(hg38): chr5:180261683-180280608:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009693
MONDO name: plasma cell myeloma
Disease details: multiple myeloma / MM
Disease DO ID:
 9538
Disease MeSH ID:
 D009101
Disease NCIt ID:
 C3242
Disease ICD11 ID:
 1582389689; 526287100
Disease OMIM ID:
 254500
Species: Human
Species details: Homo sapiens
Tissue specimen:

bone marrow plasma cells (BMPCs)
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Bioinformatics Analysis; Survival Analysis; Clinical Sample Validation
Clinical significance:

High circ_0001566 expression was associated with a short OS; circ_0001566 was decreased in CR versus NR and associated with ORR.
Description:

circ_0001566 is downregulated in CR versus NR MM cases (and in ORR versus non-ORR). Clinically, higher circ_0001566 expression predicts worse overall survival in this cohort.
Confidence score:

0.5963
Other information
Title:

Dysregulated circular RNAs are closely linked to multiple myeloma prognosis, with circ_0026652 predicting bortezomib‑based treatment response and survival via the microRNA‑608‑mediated Wnt/beta‑catenin pathway.

Journal: Oncology reports
Published: 2022
PubMed ID: 36129153
Study type:

combined biological and clinical study
Data availability: -
Code availability: -