| Expression pattern: |
DN |
| Associated gene: |
- |
| Associated microRNA: |
hsa-miR-744-5p, hsa-miR-576-3p, hsa-miR-661, hsa-miR-9-5p, hsa-miR-377-5p |
| Biological function: |
unknown |
| Molecular mechanism: |
Predicted circRNA-miRNA interaction (miRNA sponge hypothesis) without experimental functional validation |
| Biological pathway or process: |
ceRNA regulation (other) |
| Detected method: |
Q
S
|
| Validation methods: |
RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis |
| Clinical significance: |
Potential biomarkers for early diagnosis of cerebral infarction |
| Description: |
hsa_circRNA_101836 (host gene NFATC3) is significantly down-regulated in plasma from acute cerebral infarction patients versus controls and was validated by RT-qPCR. Bioinformatic predictions suggest it may bind several miRNAs, but the paper provides no experimental evidence for downstream targets or cellular functions. |
| Confidence score: |
0.4032 |