circRNA basic information
circBase ID: mmu_circ_0000420
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Mouse
Species details: Mus musculus
Tissue specimen:

colon tissue; colorectal tissues
Cell lines:

-
In vivo animal model:

other disease animal model
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: potential biomarker for disease progression / early prediction in inflammation-based tumorigenesis model
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
H
S
Validation methods:

RNA-seq; RT-qPCR; FISH / smFISH; Clinical Sample Validation; In Vivo Animal Model; Bioinformatics Analysis
Clinical significance:

-
Description:

mmu_circ_0000420 is continuously upregulated during inflammation-to-adenoma-to-CRC progression in the AOM-DSS mouse model and is highlighted as a candidate biomarker for predicting colorectal cancer development.
Confidence score:

0.5219
Other information
Title:

The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers.

Journal: Aging
Published: 2022
PubMed ID: 36446351
Study type:

combined biological and clinical study
Data availability: Additional Files 1 and 2
Code availability: -