circRNA basic information
circBase ID: -
Name: hsa_circ_GMPS
Synonym: circ-GMPS
Host Gene: GMPS
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007576
MONDO name: esophageal cancer
Disease details: esophageal cancer
Disease DO ID:
 5041
Disease MeSH ID:
 -
Disease NCIt ID:
 C7478
Disease ICD11 ID:
 669033105
Disease OMIM ID:
 133239
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; matched adjacent nontumor normal tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: GMPS
Associated microRNA: miR-490-3p, miR-217
Biological function: Predicted to act as a miRNA sponge; additionally, noted as a case where a miRNA target gene may also generate a circRNA that interacts with the same miRNA.
Molecular mechanism: Predicted miRNA-circRNA interaction (miRNA sponge/ceRNA-like) based on MiRanda/starBase; potential shared miRNA targeting relationship with host gene GMPS (TargetScan).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circ-GMPS is up-regulated in esophageal squamous cancer tissues and is computationally predicted to interact with miR-490-3p and miR-217. The study further notes a putative circRNA/miRNA/mRNA relationship where the host gene GMPS is also a predicted miR-217 target.
Confidence score:

0.1768
Other information
Title:

Profiling and Bioinformatic Analyses Indicate Differential circRNA and miRNA/isomiR Expression and Interactions.

Journal: BioMed research international
Published: 2018
PubMed ID: 29682564
Study type:

bioinformatics study
Data availability: -
Code availability: -