circRNA basic information
circBase ID: hsa_circ_0021087
Name: hsa_circ_LMO1
Synonym: -
Host Gene: LMO1
Genomic location(hg19): chr11:8248521-8252051:-
Genomic location(hg38): chr11:8226974-8230504:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

GC tissues; adjacent non-tumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: TFCP2L1, COL4A2, FMNL3, FGD6, PAIP2B, GRAMD1C, SLC14A1, DUOX2, THY1, DPYSL3, LY6E, FAM189A2, CMTM4, DNER, SYTL2, KIAA1324, SCNN1G, ACVR1C, SLC4A4, PRSS12, ADAM12, TGM2, C4orf19, MAP7D2, LDLR, NRP2, ELOVL6, LIPH, SERPINH1, EFEMP2, IGF2BP3, THBS1, MXRA7, AKR7A3, METTL7A, SLC26A9, IQGAP2, PLAC8, IL1RN
Associated microRNA: hsa-miR-1224-3p, hsa-miR-1276, hsa-miR-1304-5p, hsa-miR-184, hsa-miR-450b-3p, hsa-miR-769-3p, hsa-miR-517a-3p, hsa-miR-517c-3p, hsa-miR-623, hsa-miR-638, hsa-miR-1827
Biological function: -
Molecular mechanism: Construction of predicted circRNA-miRNA-mRNA network (in silico); reported as a potentially more important node due to more miRNA/target interactions.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0021087 is identified by integrated analysis of three GEO circRNA microarray datasets as down-regulated in gastric cancer tissue versus adjacent non-tumor tissue. The study predicts its miRNA interactions and builds a circRNA-miRNA-mRNA network, suggesting it may be a more central circRNA node in this network due to more predicted interactions, but no experimental validation is provided.
Confidence score:

0.1768
Other information
Title:

Identification of Key Genes and Circular RNAs in Human Gastric Cancer.

Journal: Medical science monitor : international medical journal of experimental and clinical research
Published: 2019
PubMed ID: 30948703
Study type:

bioinformatics study
Data availability: GSE83521; GSE89143; GSE93541; GSE19826; GSE54129; GSE79973
Code availability: -