| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
hsa-miR-216a-5p, hsa-miR-370-3p, hsa-miR-3160-5p |
| Biological function: |
unknown |
| Molecular mechanism: |
predicted miRNA sponge (circRNA-miRNA-mRNA network) |
| Biological pathway or process: |
MAPK (other); lipid metabolism (other); PI3K/AKT (other); cell cycle (other); p53 signaling (other); apoptosis (other) |
| Detected method: |
Q
S
|
| Validation methods: |
RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis |
| Clinical significance: |
Potential diagnostic metabolic biomarker for PCa |
| Description: |
hsa_circ_0006754 is up-regulated in prostate cancer tissues and was validated by qRT-PCR. It is predicted to function via a circRNA-miRNA-mRNA interaction network and is linked to PCa-related pathways including MAPK and lipid-related processes, implying potential biomarker relevance. |
| Confidence score: |
0.4032 |