| Expression pattern: |
DN |
| Associated gene: |
- |
| Associated microRNA: |
hsa-miR-4692 |
| Biological function: |
Downregulated by SCT in HeLa cells, associated with SCT-mediated growth inhibition and apoptosis promotion. |
| Molecular mechanism: |
Predicted interaction with hsa-miR-4692 (RegRNA prediction). |
| Biological pathway or process: |
ceRNA regulation (other); proliferation (inhibits); apoptosis (promotes) |
| Detected method: |
Q
|
| Validation methods: |
Back-Splice Junction PCR / divergent primers PCR; RT-qPCR; Bioinformatics Analysis; Transfection; Annexin V/PI Flow Cytometry; Cell Cycle Assay |
| Clinical significance: |
- |
| Description: |
circFANCB is downregulated by SCT in HeLa cervical cancer cells. The study predicts binding between circFANCB and hsa-miR-4692 and links SCT-regulated circFANCB (as part of the circRNA set) to inhibited growth and promoted apoptosis in HeLa cells. |
| Confidence score: |
0.5416 |