circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: circZNF609
Host Gene: ZNF609
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005556
MONDO name: lupus nephritis
Disease details: lupus nephritis
Disease DO ID:
 0080162
Disease MeSH ID:
 D008181
Disease NCIt ID:
 C34789
Disease ICD11 ID:
 1815692673
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

renal biopsy tissues / kidney tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Associated with LN disease activity parameters (correlative).
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

circRNA-seq; RNase R Treatment; RT-qPCR; Clinical Sample Validation
Clinical significance:

Significantly correlated with one or two clinical parameters of LN disease activity.
Description:

circZNF609 is significantly up-regulated in LN renal biopsies versus controls and shows correlations with one or two LN disease activity parameters. No specific miRNA target or downstream mechanism was experimentally established for circZNF609 in this paper.
Confidence score:

0.5129
Other information
Title:

circHLA-C Plays an Important Role in Lupus Nephritis by Sponging miR-150.

Journal: Molecular therapy. Nucleic acids
Published: 2018
PubMed ID: 29499937
Study type:

combined biological and clinical study
Data availability: Supplemental Information (two figures and four tables) at https://doi.org/10.1016/j.omtn.2017.12.006
Code availability: -