circRNA basic information
circBase ID: -
Name: hsa_circ_SRCAP
Synonym: chr16:30740286-30740893|+ / Chr16: 30740287-30740893|+
Host Gene: SRCAP
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
10534
Disease MeSH ID:
-
Disease NCIt ID:
C9331
Disease ICD11 ID:
1397617262
Disease OMIM ID:
613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

gastric tumor tissues; paired adjacent non-tumor tissues

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: Predicted binding to miRNAs by sequence analysis (not experimentally validated).
Biological pathway or process:

ceRNA regulation (other)

Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; divergent primers PCR; Bioinformatics Analysis; Clinical Sample Validation

Clinical significance:

-

Description:

This circRNA (chr16:30740286-30740893|+, host gene SRCAP) was identified by RNA-seq and validated by qRT-PCR as down-regulated in gastric cancer tissues versus paired adjacent non-tumor tissues. Its downstream functional role and clinical utility were not further characterized in this study.

Confidence score:

0.5135

Other information
Title:

Circular RNA hsa_circ_0000745 may serve as a diagnostic marker for gastric cancer.

Journal: World journal of gastroenterology
Published: 2017
PubMed ID: 28974900
Study type:

combined biological and clinical study

Data availability: -
Code availability: -