circRNA basic information
circBase ID: hsa_circ_0005050
Name: hsa_circ_XPO1
Synonym: -
Host Gene: XPO1
Genomic location(hg19): chr2:61712902-61717911:-
Genomic location(hg38): chr2:61485767-61490776:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0004958
MONDO name: oral cavity squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Disease DO ID:
0050866
Disease MeSH ID:
-
Disease NCIt ID:
C4833
Disease ICD11 ID:
-
Disease OMIM ID:
-
Species: Human
Species details: Homo sapiens
Tissue specimen:

OSCC tissues; normal oral mucosal tissues

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified

Detected method:
Q
S
Validation methods:

circRNA-seq; RT-qPCR; Sanger Sequencing; RNase R Treatment; Clinical Sample Validation; Bioinformatics Analysis

Clinical significance:

-

Description:

hsa_circ_0005050 (from host gene XPO1) was identified as a differentially expressed circRNA in OSCC tissues versus normal oral mucosa and was validated/confirmed as circular by RNase R treatment and Sanger sequencing; no specific downstream miRNA/target axis or functional phenotype was established for this circRNA in this study.

Confidence score:

0.5841

Other information
Title:

Expression Profile of Circular RNAs in Oral Squamous Cell Carcinoma.

Journal: Frontiers in oncology
Published: 2020
PubMed ID: 33330021
Study type:

combined biological and clinical study

Data availability: GSE131182
Code availability: -