circRNA basic information
circBase ID: hsa_circ_0001866
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr9:86293355-86297981:-
Genomic location(hg38): chr9:83678440-83683066:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent normal mucosal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: COL4A1
Associated microRNA: hsa-miR-421
Biological function: May play central roles in regulating the development of GC (inferred from ceRNA axis construction).
Molecular mechanism: ceRNA mechanism (circRNA-miRNA-mRNA network).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This study’s constructed ceRNA network suggests hsa_circ_0001866 may act as a miRNA sponge for hsa-miR-421, thereby potentially affecting COL4A1 regulation in gastric cancer/gastric adenocarcinoma. The evidence is based on microarray differential expression and bioinformatics interaction predictions without experimental validation.
Confidence score:

0.1768
Other information
Title:

Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma.

Journal: Mediators of inflammation
Published: 2020
PubMed ID: 32801999
Study type:

bioinformatics study
Data availability: GSE83521; GSE78091; GSE33651
Code availability: -