circRNA basic information
circBase ID: hsa_circ_0001936
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chrX:79962925-79975155:-
Genomic location(hg38): chrX:80707426-80719656:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent normal lung tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: CAV2, FGD5, S1PR1
Associated microRNA: has-miR-142-5p
Biological function: might play key roles in LUAD progression by regulating GTPase activity
Molecular mechanism: ceRNA (circRNA-miRNA-mRNA): hsa_circ_0001936 sponges has-miR-142-5p and might regulate CAV2, FGD5 and S1PR1
Biological pathway or process:

ceRNA regulation (other); other pathway/process (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001936 was identified as a LUAD-associated differentially expressed circRNA in the ceRNA network. The study suggests it interacts with has-miR-142-5p and may regulate target genes (CAV2/FGD5/S1PR1) linked to GTPase activity, potentially contributing to LUAD progression.
Confidence score:

0.1768
Other information
Title:

Prognostic Nomogram Based on Circular RNA-Associated Competing Endogenous RNA Network for Patients with Lung Adenocarcinoma.

Journal: Oxidative medicine and cellular longevity
Published: 2021
PubMed ID: 34497684
Study type:

bioinformatics study
Data availability: GSE101586; GSE101684
Code availability: -