circRNA basic information
circBase ID: hsa_circ_0074530
Name: hsa_circ_CD74
Synonym: -
Host Gene: CD74
Genomic location(hg19): chr5:149784242-149784743:-
Genomic location(hg38): chr5:150404679-150405180:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid carcinoma
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tumor tissues; tumor-adjacent normal thyroid tissues; whole blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-4677-5p, hsa-miR-7161-3p, hsa-miR-515-3p, hsa-miR-1271-3p, hsa-miR-3663-5p
Biological function: unknown
Molecular mechanism: Predicted ceRNA mechanism via miRNA response elements (bioinformatics).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0074530 is up-regulated in papillary thyroid carcinoma and was validated in both thyroid tissues and whole blood. This study only provided bioinformatic prediction of its miRNA response elements without experimental functional validation.
Confidence score:

0.4032
Other information
Title:

Circular RNA profiling reveals a potential role of hsa_circ_IPCEF1 in papillary thyroid carcinoma.

Journal: Molecular medicine reports
Published: 2021
PubMed ID: 34165176
Study type:

combined biological and clinical study
Data availability: GSE173299
Code availability: -