circRNA basic information
circBase ID: hsa_circ_0049271
Name: hsa_circ_KEAP1
Synonym: -
Host Gene: KEAP1
Genomic location(hg19): chr19:10610070-10610756:-
Genomic location(hg38): chr19:10499394-10500080:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009807
MONDO name: osteosarcoma
Disease details: osteosarcoma
Disease DO ID:
 3347
Disease MeSH ID:
 D012516
Disease NCIt ID:
 C9145
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

primary osteosarcoma tissues; adjacent tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Might be a tumor inhibitor in osteosarcoma.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This study found hsa_circ_0049271 to be down-regulated in osteosarcoma tissues in a circRNA microarray dataset, suggesting a potential tumor-inhibitory role, without mechanistic or experimental validation.
Confidence score:

0.1768
Other information
Title:

Construction of a circRNA-miRNA-mRNA Regulatory Network Reveals Potential Mechanism and Treatment Options for Osteosarcoma.

Journal: Frontiers in genetics
Published: 2021
PubMed ID: 34079579
Study type:

bioinformatics study
Data availability: GSE140256; GSE28423; GSE99671; https://www.ncbi.nlm.nih.gov/geo/; https://portal.gdc.cancer.gov/
Code availability: -