circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_004183
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0011368
MONDO name: papillary thyroid Microcarcinoma
Disease details: papillary thyroid microcarcinoma
Disease DO ID:
 -
Disease MeSH ID:
 C563277
Disease NCIt ID:
 C46004
Disease ICD11 ID:
 -
Disease OMIM ID:
 603744
Species: Human
Species details: Homo sapiens
Tissue specimen:

serum
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-7162-5p, hsa-miR-6875-3p, hsa-miR-516b-3p, hsa-miR-516a-3p, hsa-miR-4687-3p
Biological function: unknown
Molecular mechanism: Predicted miRNA sponge interactions (targets miR-7162-5p/miR-6875-3p/miR-516b-3p/miR-516a-3p/miR-4687-3p).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

Serum hsa_circRNA_004183 is down-regulated in PTMC (L) versus non-invasive PTMC in female patients, validated by RT-qPCR. It is predicted to bind several miRNAs, suggesting possible ceRNA-related involvement in lymph node metastasis, though no specific downstream target is validated.
Confidence score:

0.4032
Other information
Title:

Correlation between serum circRNA and thyroid micropapillary carcinoma with cervical lymph node metastasis.

Journal: Medicine
Published: 2020
PubMed ID: 33217846
Study type:

combined biological and clinical study
Data availability: -
Code availability: -