| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
Diagnostic tissue biomarker; excluded from Cox regression analyses for BCR due to very low expression and limited assay performance. |
| Molecular mechanism: |
not specified |
| Biological pathway or process: |
not specified |
| Detected method: |
Q
M
|
| Validation methods: |
Microarray; RT-qPCR; RNase R Treatment; Sanger Sequencing; Clinical Sample Validation; ROC Analysis; Cohort Study |
| Clinical significance: |
Upregulated in tumor vs adjacent normal tissue; modest discrimination (AUC 0.634) with limited detectability (only 45/79 pairs). |
| Description: |
circNEAT1 is up-regulated in prostate cancer tissue but has very low abundance and poorer RT-qPCR performance, leading to exclusion from multivariable BCR prognostic modeling in this study. Its role here is primarily as a diagnostic expression marker rather than a mechanistically characterized regulator. |
| Confidence score: |
0.6663 |