circRNA basic information
circBase ID: -
Name: hsa_circ_BNC2
Synonym: circBNC2
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004958
MONDO name: oral cavity squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Disease DO ID:
 0050866
Disease MeSH ID:
 -
Disease NCIt ID:
 C4833
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent normal tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Back-Splice Junction PCR / divergent primers PCR; Sanger Sequencing
Clinical significance:

-
Description:

circBNC2 was identified from OSCC tumor vs adjacent normal RNA-seq data and showed reduced expression in tumors; its existence and tumor-associated differential expression were supported by divergent-primer PCR and Sanger sequencing, but no further functional or mechanistic characterization was reported.
Confidence score:

0.385
Other information
Title:

circRNAome Profiling in Oral Carcinoma Unveils a Novel circFLNB that Mediates Tumour Growth-Regulating Transcriptional Response.

Journal: Cells
Published: 2020
PubMed ID: 32785098
Study type:

combined biological and clinical study
Data availability: -
Code availability: -