circRNA basic information
circBase ID: hsa_circ_0058087
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr2:216236631-216253024:-
Genomic location(hg38): chr2:215371908-215388301:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; background normal liver tissues; tumour specimens; para-tumour normal background liver tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Survival Analysis
Clinical significance:

Low expression of hsa_circ_0058087 in HCC tissues is associated with inferior RFS and OS; low expression is an independent predictive factor for inferior RFS in multivariate analysis.
Description:

hsa_circ_0058087 is down-regulated in HCC and has prognostic significance: lower expression in tumor tissue correlates with worse recurrence-free and overall survival, and is an independent predictor for inferior RFS.
Confidence score:

0.4679
Other information
Title:

Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue.

Journal: Scientific reports
Published: 2021
PubMed ID: 33727578
Study type:

combined biological and clinical study
Data availability: Supplementary material available at 10.1038/s41598-021-85237-y.
Code availability: -