circRNA basic information
circBase ID: hsa_circ_0008221
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr12:11199618-11273779:-
Genomic location(hg38): chr12:11047019-11121180:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

AGS
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: May act as a node in a circRNA-miRNA-mRNA ceRNA network under esomeprazole treatment in gastric cancer cells.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0008221 was highlighted as a potential key node in the circRNA-miRNA-mRNA ceRNA network altered in AGS gastric cancer cells after esomeprazole treatment, based on microarray profiling and bioinformatic network construction.
Confidence score:

0.1768
Other information
Title:

Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA-miRNA-mRNA ceRNA networks.

Journal: Oncology letters
Published: 2020
PubMed ID: 33101498
Study type:

biological research
Data availability: available from the corresponding author on reasonable request
Code availability: -