circRNA basic information
circBase ID: hsa_circ_0031408
Name: hsa_circ_STXBP6
Synonym: -
Host Gene: STXBP6
Genomic location(hg19): chr14:25443870-25444056:-
Genomic location(hg38): chr14:24974664-24974850:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: Prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PCa tissues; normal adjacent prostatic tissues
Cell lines:

PC-3; RWPE-1
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-145, hsa-miR-182, hsa-miR-192, hsa-miR-215, hsa-miR-335, hsa-miR-338-3p, hsa-miR-502-5p, hsa-miR-513a-3p, hsa-miR-890
Biological function: unknown
Molecular mechanism: Predicted miRNA response elements (MREs) and downstream target-gene enrichment; no specific validated axis reported.
Biological pathway or process:

cell cycle (other); other pathway/process (other)
Detected method:
Q
M
Validation methods:

Microarray; Bioinformatics Analysis; divergent primers PCR; RT-qPCR
Clinical significance:

-
Description:

hsa_circ_0031408 is up-regulated in PC-3 prostate cancer cells versus RWPE-1. Its miRNA response elements and potential target genes were predicted bioinformatically, with enrichment including cell-cycle-related pathways, but no specific downstream miRNA-mRNA axis was highlighted as a main predicted axis in the paper.
Confidence score:

0.3858
Other information
Title:

Identification of Prostate Cancer-Related Circular RNA Through Bioinformatics Analysis.

Journal: Frontiers in genetics
Published: 2020
PubMed ID: 32922436
Study type:

combined biological and clinical study
Data availability: GSE140927; TCGA
Code availability: -