circRNA basic information
circBase ID: hsa_circ_0049783
Name: hsa_circ_CLEC17A
Synonym: -
Host Gene: CLEC17A
Genomic location(hg19): chr19:14705328-14705612:+
Genomic location(hg38): chr19:14594516-14594800:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0006047
MONDO name: pancreatic adenocarcinoma
Disease details: pancreatic adenocarcinoma
Disease DO ID:
 4074
Disease MeSH ID:
 -
Disease NCIt ID:
 C8294
Disease ICD11 ID:
 1663659989
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PAAD tissue; normal pancreatic tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-mir-324-3p
Biological function: May modulate PAAD biogenesis, growth and progression via a circRNA/miRNA axis (circ-CLEC17A/hsa-mir-324-3p).
Molecular mechanism: ceRNA-like circRNA/miRNA interaction (circ-CLEC17A with hsa-mir-324-3p); downstream targets not specified.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

circ-CLEC17A is aberrantly overexpressed in PAAD tissues from females compared to males.
Description:

circ-CLEC17A (hsa_circ_0049783) is up-regulated in PAAD and included in the constructed ceRNA network, with a proposed circ-CLEC17A/hsa-mir-324-3p axis. It also shows higher expression in female PAAD tissues than in males in the analyzed dataset.
Confidence score:

0.1768
Other information
Title:

CircUBAP2-mediated competing endogenous RNA network modulates tumorigenesis in pancreatic adenocarcinoma.

Journal: Aging
Published: 2019
PubMed ID: 31584877
Study type:

bioinformatics study
Data availability: GSE79634; GSE69362; GSE60980
Code availability: -