circRNA basic information
circBase ID: hsa_circ_0000711
Name: hsa_circ_NFATC3
Synonym: -
Host Gene: NFATC3
Genomic location(hg19): chr16:68155889-68160513:+
Genomic location(hg38): chr16:68121986-68126610:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0000960
MONDO name: diabetic peripheral angiopathy
Disease details: diabetic foot ulcer
Disease DO ID:
11713
Disease MeSH ID:
D003925
Disease NCIt ID:
C35610
Disease ICD11 ID:
-
Disease OMIM ID:
-
Species: Human
Species details: Homo sapiens
Tissue specimen:

DFU tissues; non-DFU tissues

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DS
Associated gene: NFATC3
Associated microRNA: -
Biological function: Included as a differentially expressed circRNA in DFU ceRNA network (bioinformatics-based)
Molecular mechanism: ceRNA network component (predicted circRNA-miRNA-mRNA regulation) in DFU
Biological pathway or process:

ceRNA regulation (other)

Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis

Clinical significance:

-

Description:

hsa_circ_0000711 (host gene NFATC3) was one of the eight differentially expressed circRNAs used to construct a DFU-related ceRNA network using GEO datasets. The article did not report specific validated interacting miRNAs/mRNAs or functional experiments for this circRNA.

Confidence score:

0.1768

Other information
Title:

Integrated analysis of circRNA-miRNA-mRNA regulatory network identifies potential diagnostic biomarkers in diabetic foot ulcer.

Journal: Non-coding RNA research
Published: 2020
PubMed ID: 32913938
Study type:

bioinformatics study

Data availability: GSE114248; GSE84971; GSE80178; GSE132187
Code availability: -