circRNA basic information
circBase ID: hsa_circ_0001222
Name: hsa_circ_FBXO7
Synonym: -
Host Gene: FBXO7
Genomic location(hg19): chr22:32874967-32881196:+
Genomic location(hg38): chr22:32478980-32485209:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0000960
MONDO name: diabetic peripheral angiopathy
Disease details: diabetic foot ulcer
Disease DO ID:
 11713
Disease MeSH ID:
 D003925
Disease NCIt ID:
 C35610
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

DFU tissues; non-DFU tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: FBXO7
Associated microRNA: -
Biological function: Included as a differentially expressed circRNA in DFU ceRNA network (bioinformatics-based)
Molecular mechanism: ceRNA network component (predicted circRNA-miRNA-mRNA regulation) in DFU
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001222 (host gene FBXO7) was included among the differentially expressed circRNAs used to build a DFU-associated ceRNA network from GEO datasets. The study did not report a specific validated miRNA/mRNA axis or functional experiments for this circRNA.
Confidence score:

0.1768
Other information
Title:

Integrated analysis of circRNA-miRNA-mRNA regulatory network identifies potential diagnostic biomarkers in diabetic foot ulcer.

Journal: Non-coding RNA research
Published: 2020
PubMed ID: 32913938
Study type:

bioinformatics study
Data availability: GSE114248; GSE84971; GSE80178; GSE132187
Code availability: -