circRNA basic information
circBase ID: hsa_circ_0000512
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr14:20811282-20811436:-
Genomic location(hg38): chr14:20343123-20343277:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: hsa_circ_0000512 was identified as upregulated in CRC tissues during the circRNA screening/validation stage, but no functional role was experimentally characterized.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis; Microarray
Clinical significance:

-
Description:

hsa_circ_0000512 was detected in the intersecting GEO datasets and validated by RT-qPCR as upregulated in CRC tissues. The study did not further characterize its clinical significance, interaction partners, subcellular localization, or functional mechanism.
Confidence score:

0.4032
Other information
Title:

Sevoflurane suppresses colorectal cancer malignancy by modulating beta-catenin ubiquitination degradation via circSKA3.

Journal: Cellular signalling
Published: 2024
PubMed ID: 38029946
Study type:

combined biological and clinical study
Data availability: GSE126094; GSE138589; GSE442837
Code availability: -