circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circHIPK3
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0012727
MONDO name: Kawasaki disease
Disease details: Kawasaki disease
Disease DO ID:
 13378
Disease MeSH ID:
 D009080
Disease NCIt ID:
 C34825
Disease ICD11 ID:
 540285662
Disease OMIM ID:
 611775
Species: Human
Species details: Homo sapiens
Tissue specimen:

coronary artery tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: possible molecular biomarker to reflect the status of Kawasaki disease
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

possible molecular markers for Kawasaki disease
Description:

circHIPK3 is significantly down-regulated in coronary artery tissue from untreated Kawasaki disease patients and returns to normal levels after treatment, suggesting potential utility as a disease-status biomarker. This study does not experimentally validate a specific mechanistic axis for circHIPK3 in Kawasaki disease.
Confidence score:

0.1768
Other information
Title:

Analysis of Circular RNAs in the Coronary Arteries of Patients with Kawasaki Disease.

Journal: Journal of lipid and atherosclerosis
Published: 2019
PubMed ID: 32821699
Study type:

bioinformatics study
Data availability: GSE64486
Code availability: -