circRNA basic information
circBase ID: hsa_circ_0003187
Name: hsa_circ_ZNF827
Synonym: -
Host Gene: ZNF827
Genomic location(hg19): chr4:146767107-146770713:-
Genomic location(hg38): chr4:145845955-145849561:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008903
MONDO name: lung cancer
Disease details: lung cancer
Disease DO ID:
 1324
Disease MeSH ID:
 -
Disease NCIt ID:
 C7377
Disease ICD11 ID:
 -
Disease OMIM ID:
 211980
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

A549; NCI-H1299
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: Predicted circRNA-miRNA interactions (bioinformatics); downstream effects not experimentally validated for this circRNA.
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0003187 is significantly up-regulated in irradiated NSCLC cells (A549; also measured in NCI-H1299) compared with non-irradiated controls. The study did not experimentally validate a specific downstream mechanism for this circRNA beyond predicted circRNA-miRNA interactions.
Confidence score:

0.2465
Other information
Title:

RNAseq profiling of circRNA expression in radiation-treated A549 cells and bioinformatics analysis of radiation-related circRNA-miRNA networks.

Journal: Oncology letters
Published: 2020
PubMed ID: 32724397
Study type:

biological research
Data availability: GSE124396
Code availability: -