circRNA basic information
circBase ID: hsa_circ_0058097
Name: hsa_circ_FN1
Synonym: hsa-CircRNA_058097
Host Gene: FN1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0006890
MONDO name: parathyroid gland adenoma
Disease details: sporadic parathyroid adenomas
Disease DO ID:
 7608
Disease MeSH ID:
 -
Disease NCIt ID:
 C156757
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

parathyroid adenoma tissue; normal parathyroid tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR_876-3p, hsa-miR_1231, hsa-miR_1238, hsa-miR_515-5p, hsa-miR_558
Biological function: -
Molecular mechanism: miRNA sponging (predicted)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis; RNase R Treatment
Clinical significance:

-
Description:

hsa-CircRNA_058097 is significantly down-regulated in sporadic parathyroid adenomas versus normal parathyroid tissue and has predicted miRNA binding sites, suggesting it may participate in miRNA-mediated regulatory networks in PA.
Confidence score:

0.5135
Other information
Title:

A Role for Circular Non-Coding RNAs in the Pathogenesis of Sporadic Parathyroid Adenomas and the Impact of Gender-Specific Epigenetic Regulation.

Journal: Cells
Published: 2018
PubMed ID: 30598042
Study type:

combined biological and clinical study
Data availability: -
Code availability: -