circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_0263
Host Gene: rno-miR-29b-5p, rno-miR-29b-3p
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: atrial fibrosis
Species: rat
Species details: rat
Sample type: tissue, cell line
Sample type details: rat atrial fibroblasts
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: COL-1, COL-3, MMP2 and MMP9
Associated microRNA: rno-miR-29b-5p, rno-miR-29b-3p
Biological function: circRNA_0263 overexpression significantly enhanced the cell viability of fibroblasts; while circRNA_0263 knockdown inhibited the cell viability compared to the si-NC group
Molecular mechanism: circRNA_0263/miR-29b axis
Survival: -
Supported No.:
 1
Description:

Among the dysregulated circRNAs, circRNA_0263 and circRNA_1507 were the most upregulated and most downregulated circRNAs, respectively.
Other information
Title:

CircRNA_0263 and circRNA_1507 are dysregulated in a rat model of atrial fibrosis induced by chronic intermittent hypoxia.

Journal: Am J Transl Res
Published: 2023/2/14
PubMed ID: 36777857