circRNA basic information
circBase ID: hsa_circ_0046906
Name: hsa_circ_VAPA
Synonym: -
Host Gene: VAPA
Genomic location(hg19): chr18:9913954-9914332:+
Genomic location(hg38): chr18:9913957-9914335:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

NSCLC tissues; adjacent non-tumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation
Clinical significance:

hsa_circ_0046906 was significantly higher in NSCLC tissues than in adjacent non-tumor tissues.
Description:

hsa_circ_0046906 is one of the VAPA-derived circVAPA isoforms screened in NSCLC tissues. It was significantly up-regulated in NSCLC tissues compared with adjacent non-tumor tissues, but the article did not perform further functional or mechanistic assays for this isoform.
Confidence score:

0.2995
Other information
Title:

CircVAPA exerts oncogenic property in non-small cell lung cancer by the miR-876-5p/WNT5A axis.

Journal: The journal of gene medicine
Published: 2021
PubMed ID: 33619796
Study type:

clinical study
Data availability: The datasets used during the present study are available from the corresponding author upon reasonable request.
Code availability: -