circRNA basic information
circBase ID: hsa_circ_0000367
Name: hsa_circ_SIAE
Synonym: hsa_circRNA_000367
Host Gene: SIAE
Genomic location(hg19): chr11:124517260-124518071:-
Genomic location(hg38): chr11:124647364-124648175:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004986
MONDO name: urinary bladder carcinoma
Disease details: bladder cancer
Disease DO ID:
 4007
Disease MeSH ID:
 -
Disease NCIt ID:
 C4912
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

BCa tissue; para-carcinoma normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: miR-331-3p, miR-4646-5p, miR-4797-5p, miR-3919, miR-3190-3p
Biological function: unknown
Molecular mechanism: Predicted miRNA sponge (MRE prediction) in BCa
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RNase R Treatment; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Early T stage had a positive correlation with the expression of hsa_circRNA_000367.
Description:

hsa_circRNA_000367 is down-regulated in bladder cancer tissues versus paired para-carcinoma normal tissues (microarray and RT-qPCR validation). The study predicts it may sponge miRNAs including miR-331-3p, miR-4646-5p, miR-4797-5p, miR-3919 and miR-3190-3p. Higher hsa_circRNA_000367 expression correlates with earlier T stage.
Confidence score:

0.5135
Other information
Title:

Microarray Expression Profiles and Bioinformatics Analyses Reveal Aberrant Circular RNAs Expression in Bladder Cancer.

Journal: OncoTargets and therapy
Published: 2020
PubMed ID: 33149606
Study type:

combined biological and clinical study
Data availability: Supplementary data 1; Supplementary data 2; Supplementary data 3
Code availability: -