circRNA basic information
circBase ID: -
Name: mmu_circ_Zfp609
Synonym: mmu_circRNA_19523
Host Gene: Zfp609
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004975
MONDO name: Alzheimer disease
Disease details: Alzheimer’s disease
Disease DO ID:
 10652
Disease MeSH ID:
 D000544
Disease NCIt ID:
 C2866
Disease ICD11 ID:
 1611724421
Disease OMIM ID:
 -
Species: Mouse
Species details: Mus musculus
Tissue specimen:

brain
Cell lines:

-
In vivo animal model:

genetically engineered animal model
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: Possible modulation of downstream mRNAs via circRNA-miRNA-mRNA regulatory network (predicted).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray
Clinical significance:

-
Description:

mmu_circRNA_19523 is up-regulated in Tg2576 mouse brain (12 months) based on circRNA microarray. The study suggests dysregulated circRNAs may contribute to AD via predicted circRNA-miRNA-mRNA networks, without circRNA-specific mechanistic validation.
Confidence score:

0.1155
Other information
Title:

Possible epigenetic regulatory effect of dysregulated circular RNAs in Alzheimer's disease model.

Journal: Scientific reports
Published: 2019
PubMed ID: 31420566
Study type:

bioinformatics study
Data availability: Supplemental Datasets; 10.1038/s41598-019-48471-z
Code availability: -