circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA5430
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: Lung adenocarcinoma
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral whole blood / PWB
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation
Clinical significance:

Potential noninvasive biomarker for lung adenocarcinoma in peripheral whole blood.
Description:

circRNA5430 is up-regulated in peripheral whole blood of lung adenocarcinoma patients versus healthy controls, confirmed by RT-PCR/RT-qPCR in an independent validation cohort. The study suggests blood circRNAs may serve as noninvasive biomarkers, but no specific mechanism was experimentally validated for circRNA5430.
Confidence score:

0.3588
Other information
Title:

Circular RNA expression profile in peripheral whole blood of lung adenocarcinoma by high: Throughput sequencing.

Journal: Medicine
Published: 2019
PubMed ID: 31626137
Study type:

combined biological and clinical study
Data availability: -
Code availability: -