circRNA basic information
circBase ID: hsa_circ_0000825
Name: hsa_circ_MTCL1
Synonym: -
Host Gene: MTCL1
Genomic location(hg19): chr18:8718421-8720494:+
Genomic location(hg38): chr18:8718423-8720496:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

22Rv1; LNCaP; VCaP; DU145; PC-3
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: MTCL1
Associated microRNA: -
Biological function: -
Molecular mechanism: Host-gene association with MTCL1 reported; no experimental mechanism for the circRNA provided.
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0000825 is reported as the most strongly down-regulated circRNA (by fold change) between androgen-dependent and androgen-independent prostate cancer cell lines and is associated with the host gene MTCL1. The study provides no direct functional or mechanistic validation for this circRNA.
Confidence score:

0.1768
Other information
Title:

Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer.

Journal: Frontiers in cell and developmental biology
Published: 2021
PubMed ID: 33718350
Study type:

bioinformatics study
Data availability: The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.; https://www.frontiersin.org/articles/10.3389/fcell.2021.605686/full#supplementary-material
Code availability: -