circRNA basic information
circBase ID: hsa_circ_0136474
Name: hsa_circ_ASH2L
Synonym: circ_0136474
Host Gene: hsa-miR-127-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP-13
Associated microRNA: hsa-miR-127-5p
Biological function: suppressed cell proliferation
Molecular mechanism: facilitating MMP-13 expression and suppressing hsa-miR-127-5p expression
Survival: -
Supported No.:
 2
Description:

Circ_0136474 and MMP-13 suppressed cell proliferation, while enhanced cell apoptosis by competitive binding to miR-127-5p in OA.
Other information
Title:

Circ_0136474 and MMP-13 suppressed cell proliferation by competitive binding to miR-127-5p in osteoarthritis.

Journal: J Cell Mol Med
Published: 2019/8/14
PubMed ID: 31402547