circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_101252
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0015459
MONDO name: nasopharyngeal carcinoma
Disease details: nasopharyngeal carcinoma
Disease DO ID:
 9261
Disease MeSH ID:
 D00007727; D000077274
Disease NCIt ID:
 C3871
Disease ICD11 ID:
 1883313543
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

nasopharyngeal tissue; NPC tissue; chronic nasopharyngitis tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: ITGB8, MPZL1
Associated microRNA: hsa-miR-145-5p
Biological function: -
Molecular mechanism: Predicted circRNA-miRNA-mRNA regulatory network (miRNA sponge/ceRNA) involving hsa-miR-145-5p and downstream mRNAs ITGB8 and MPZL1.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RNase R Treatment; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circRNA_101252 is up-regulated in NPC tissue and was validated by RT-qPCR. It was placed into a predicted ceRNA network where it may bind hsa-miR-145-5p and associate with mRNAs including ITGB8 and MPZL1.
Confidence score:

0.5135
Other information
Title:

Integrated analysis of transcriptome profiling predicts potential lncRNA and circRNA targets in human nasopharyngeal carcinoma.

Journal: Oncology letters
Published: 2020
PubMed ID: 32218863
Study type:

combined biological and clinical study
Data availability: All data generated or analyzed during this study are included in this published article.
Code availability: -