circRNA basic information
circBase ID: -
Name: hsa_circ_ANKRD12
Synonym: hsa_circ_102296
Host Gene: ANKRD12
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0100481
MONDO name: active tuberculosis
Disease details: active tuberculosis
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa‐miR‐578, hsa‐miR‐429, hsa‐miR‐449a, hsa‐miR‐449b‐5p, hsa‐miR‐34c‐5p
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circRNA_102296 is up-regulated in plasma from active TB patients versus healthy controls and was validated by qRT-PCR after microarray screening. It is reported to align with the host gene ANKRD12 and has predicted miRNA response elements, but no functional mechanism or clinical diagnostic analysis was reported for this circRNA.
Confidence score:

0.4032
Other information
Title:

Dysregulated circRNAs in plasma from active tuberculosis patients.

Journal: Journal of cellular and molecular medicine
Published: 2018
PubMed ID: 29961269
Study type:

combined biological and clinical study
Data availability: GSE106953
Code availability: -