circRNA basic information
circBase ID: -
Name: hsa_circ_CNOT6L
Synonym: hsa_circRNA_103670
Host Gene: CNOT6L
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005580
MONDO name: esophageal squamous cell carcinoma
Disease details: esophageal squamous cell cancer
Disease DO ID:
 3748
Disease MeSH ID:
 C562729; D000077277
Disease NCIt ID:
 C4024
Disease ICD11 ID:
 1417891145
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

esophagus cancer lesion tissue; adjacent normal-appearing esophagus tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: CNOT6L
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray
Clinical significance:

-
Description:

In ESCC tumor tissues, hsa_circRNA_103670 is identified by circRNA microarray as strongly up-regulated compared with adjacent normal-appearing esophagus tissues. It is reported to align with/derive from the host gene CNOT6L, suggesting a potential link to gene expression regulation, but no functional mechanism was experimentally validated in this study.
Confidence score:

0.1155
Other information
Title:

Profiles of differentially expressed circRNAs in esophageal and breast cancer.

Journal: Cancer management and research
Published: 2018
PubMed ID: 30087579
Study type:

combined biological and clinical study
Data availability: -
Code availability: -