circRNA basic information
circBase ID: -
Name: hsa_circ_TNFRSF21
Synonym: circ_TNFRSF21
Host Gene: TNFRSF21
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002529
MONDO name: skin squamous cell carcinoma
Disease details: Cutaneous squamous cell carcinoma
Disease DO ID:
 3151
Disease MeSH ID:
 -
Disease NCIt ID:
 C4819
Disease ICD11 ID:
 1448983042
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

skin biopsies
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Clinical Sample Validation
Clinical significance:

-
Description:

circ_TNFRSF21 is significantly up-regulated in cSCC versus healthy skin and is validated in an expanded clinical cohort by NanoString. The paper suggests its expression may be co-regulated with its host gene TNFRSF21, but does not report a specific downstream mechanism.
Confidence score:

0.2995
Other information
Title:

A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.

Journal: Scientific reports
Published: 2020
PubMed ID: 32108138
Study type:

combined biological and clinical study
Data availability: GSE139505
Code availability: -