circRNA basic information
circBase ID: hsa_circ_0001776
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:158552176-158557544:-
Genomic location(hg38): chr7:158759485-158764853:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005580
MONDO name: esophageal squamous cell carcinoma
Disease details: oesophageal squamous cell carcinoma / ESCC
Disease DO ID:
 3748
Disease MeSH ID:
 C562729; D000077277
Disease NCIt ID:
 C4024
Disease ICD11 ID:
 1417891145
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

ESCC tissues; adjacent non-cancer tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: 197 target genes
Associated microRNA: hsa-miR-497-5p, hsa-miR-195-5p, hsa-miR-4661-5p, hsa-miR-450b-5p, hsa-miR-1269a, hsa-miR-338-3p, hsa-miR-424-5p
Biological function: May act as a ceRNA in an ESCC circRNA-miRNA-mRNA coexpression network.
Molecular mechanism: Predicted ceRNA mechanism within a circRNA-miRNA-mRNA network.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

circRNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001776 was identified as one of five dysregulated circRNAs in an ESCC circRNA-associated ceRNA network. It was supported by circRNA sequencing and qRT-PCR validation of selected circRNAs, but its individual host gene, expression direction and precise miRNA pairing were not specified in the provided text.
Confidence score:

0.4685
Other information
Title:

RNA sequencing reveals the implication of the circRNA-associated ceRNA network in oesophageal squamous cell carcinoma.

Journal: Carcinogenesis
Published: 2023
PubMed ID: 37402652
Study type:

combined bioinformatics and clinical study
Data availability: The data underlying this article will be shared on reasonable request to the corresponding author; TCGA
Code availability: -