circRNA basic information
circBase ID: hsa_circ_0002872
Name: hsa_circ_PTPRM
Synonym: -
Host Gene: PTPRM
Genomic location(hg19): chr18:8113483-8143777:+
Genomic location(hg38): chr18:8113485-8143779:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008903
MONDO name: lung cancer
Disease details: lung cancer
Disease DO ID:
 1324
Disease MeSH ID:
 -
Disease NCIt ID:
 C7377
Disease ICD11 ID:
 -
Disease OMIM ID:
 211980
Species: Human
Species details: Homo sapiens
Tissue specimen:

serum; lung cancer tissues; adjacent normal tissues / paracancerous tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: ZBTB46
Associated microRNA: hsa-miR-29b-1-5p
Biological function: May influence lung cancer progression (predicted via ceRNA axis).
Molecular mechanism: Predicted ceRNA mechanism: hsa_circ_0002872 sponges hsa-miR-29b-1-5p to regulate ZBTB46.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0002872 is down-regulated in lung cancer tissues versus adjacent tissues. The study predicts a ceRNA axis where hsa_circ_0002872 sponges hsa-miR-29b-1-5p to regulate ZBTB46, potentially influencing lung cancer progression.
Confidence score:

0.4032
Other information
Title:

hsa_circ_0002872 functions in lung cancer prognostic and tumorigenesis through regulating ZBTB46 via sponging hsa-miR-29b-1-5p.

Journal: Clinics (Sao Paulo, Brazil)
Published: 2025
PubMed ID: 40780118
Study type:

combined biological and clinical study
Data availability: TCGA; CPTAC; HPA
Code availability: -