circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_400031
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

cancer tissues; paired adjacent non-cancerous tissues; tumor tissue; matched non-tumor tissue; HCC tissues; paired paracancerous tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

CircDA predicted hsa_circRNA_400031 to be associated with HCC, and RT-qPCR in paired human HCC vs paracancerous tissues showed it is significantly up-regulated in HCC.
Confidence score:

0.2995
Other information
Title:

A computational model of circRNA-associated diseases based on a graph neural network: prediction and case studies for follow-up experimental validation.

Journal: BMC biology
Published: 2024
PubMed ID: 38281919
Study type:

combined biological and clinical study
Data availability: Zenodo (https://zenodo.org/record/8079147); http://server.malab.cn/CircDA; https://github.com/nmt315320/CircDA.git
Code availability: https://github.com/nmt315320/CircDA.git