circRNA basic information
circBase ID: hsa_circ_0006089
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr2:9490936-9499018:+
Genomic location(hg38): chr2:9350807-9358889:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: Gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

GC tissues; normal tissues; cancerous tissues; paired non-neoplastic tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: FNDC1, HTRA1, IER5 L, IFIT2, NDUFA4L2, SERPINE1
Associated microRNA: hsa-miR-765, hsa-miR-198, hsa-miR-125a-3 p, hsa-miR-486-5 p
Biological function: Associated with gastric cancer progression and prognosis as a component of the ceRNA prognostic subnetwork.
Molecular mechanism: Predicted ceRNA mechanism in a circRNA-miRNA-mRNA regulatory subnetwork.
Biological pathway or process:

ceRNA regulation (other); PI3K/AKT (other); p53 signaling (other); HIF-1 signaling (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis; Survival Analysis
Clinical significance:

Potential prognostic biomarker in gastric cancer.
Description:

hsa_circ_0006089 was identified and RT-qPCR-validated as up-regulated in gastric cancer tissues. It was included in the predicted prognostic ceRNA subnetwork associated with gastric cancer progression and prognosis.
Confidence score:

0.5047
Other information
Title:

A comprehensive analysis of the circRNA, miRNA, and mRNA networks reveals prognostic biomarkers for gastric cancer.

Journal: Zeitschrift fur Gastroenterologie
Published: 2026
PubMed ID: 41862194
Study type:

combined biological and clinical study
Data availability: GSE83521; GSE23739; GSE26899; TCGA
Code availability: -