circRNA basic information
circBase ID: hsa_circ_0001020
Name: hsa_circ_UGP2
Synonym: -
Host Gene: UGP2
Genomic location(hg19): chr2:64083439-64085070:+
Genomic location(hg38): chr2:63856305-63857936:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissues; matched adjacent non-tumorous tissues; adjacent chronic hepatitis tissues; HCC tissues
Cell lines:

Huh-7; HepG2; SK-Hep-1; QGY-7703
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: No specific biological function was established; hsa_circ_0001020 was significantly decreased in HCC tissues and lower expression was associated with shorter OS.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Sanger Sequencing; Actinomycin D / DRB Stability Assay; RNase R Treatment; Survival Analysis; Bioinformatics Analysis
Clinical significance:

Lower hsa_circ_0001020 expression was associated with shorter OS in HCC patients.
Description:

hsa_circ_0001020 is down-regulated in HCC tissues compared with adjacent non-tumorous tissues. Lower expression was associated with shorter overall survival, but no disease mechanism or biological function was further characterized in this study.
Confidence score:

0.6841
Other information
Title:

Circular RNA hsa_circ_0098181 inhibits metastasis in hepatocellular carcinoma by activating the Hippo signaling pathway via interaction with eEF2.

Journal: Annals of hepatology
Published: 2023
PubMed ID: 37286166
Study type:

combined biological and clinical study
Data availability: GSE121714
Code availability: -