circRNA basic information
circBase ID: -
Name: hsa_circ_CHD2
Synonym: circCHD2
Host Gene: CHD2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005406
MONDO name: gestational diabetes
Disease details: gestational diabetes mellitus / GDM
Disease DO ID:
 11714
Disease MeSH ID:
 D016640
Disease NCIt ID:
 C34942
Disease ICD11 ID:
 1320503631
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

placentas / placental tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Sanger Sequencing; RNase R Treatment; Actinomycin D / DRB Stability Assay; Clinical Sample Validation
Clinical significance:

-
Description:

circCHD2 was identified as significantly up-regulated in GDM placentas; it was validated by qRT-PCR and further used to demonstrate circRNA properties such as RNase R resistance and higher stability compared with its linear transcript.
Confidence score:

0.5909
Other information
Title:

Identification of human placenta-derived circular RNAs and autophagy related circRNA-miRNA-mRNA regulatory network in gestational diabetes mellitus.

Journal: Frontiers in genetics
Published: 2022
PubMed ID: 36531251
Study type:

combined biological and clinical study
Data availability: GSE206041
Code availability: -