circRNA basic information
circBase ID: hsa_circ_0021412
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr11:18010143-18029623:-
Genomic location(hg38): chr11:17988596-18008076:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor specimens
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0021412 is up-regulated in HCC tumors with TERT promoter mutations compared with wildtype TERT promoter tumors, and its differential expression was validated by qPCR in the validation cohort. The study did not define a specific downstream miRNA/mRNA axis or mechanism for hsa_circ_0021412.
Confidence score:

0.4032
Other information
Title:

Integrated Analysis of Altered lncRNA, circRNA, microRNA, and mRNA Expression in Hepatocellular Carcinoma Carrying TERT Promoter Mutations.

Journal: Journal of hepatocellular carcinoma
Published: 2022
PubMed ID: 36471741
Study type:

combined biological and clinical study
Data availability: Sequence Read Archive (SRA) PRJNA808183
Code availability: -