circRNA basic information
circBase ID: hsa_circ_0001394
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr4:6925099-6925838:+
Genomic location(hg38): chr4:6923372-6924111:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; matched non-tumor tissues
Cell lines:

HepG2
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
M
Validation methods:

Microarray; RNA-seq; RT-qPCR; Clinical Sample Validation; Transfection; CCK8; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0001394 is up-regulated in HCC tissues and was validated by RT-qPCR; in vitro knockdown in HepG2 cells did not significantly change proliferation in the reported assay, and no mechanism/axis for this circRNA was established in this study.
Confidence score:

0.5817
Other information
Title:

Upregulation of hsa_circ_0002003 promotes hepatocellular carcinoma progression.

Journal: BMC cancer
Published: 2023
PubMed ID: 37400785
Study type:

combined biological and clinical study
Data availability: GSE78520; GSE94508; GSE97332; GSE76903; GSE14520; TCGA-LIHC (https://xenabrowser.net/)
Code availability: -