circRNA basic information
circBase ID: hsa_circ_0000512
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: RPPH1
Genomic location(hg19): chr14:20811282-20811436:-
Genomic location(hg38): chr14:20343123-20343277:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005005
MONDO name: clear cell renal carcinoma
Disease details: clear cell renal cell carcinoma
Disease DO ID:
 4467
Disease MeSH ID:
 -
Disease NCIt ID:
 C4033
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

ccRCC tissues; normal kidney tissues
Cell lines:

786-O; Caki-1; 293T
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; Bioinformatics Analysis; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

hsa_circ_0000512 is down-regulated in ccRCC tissues based on microarray screening and RT-qPCR validation. The study did not further define its specific miRNA/mRNA regulatory axis or functional mechanism.
Confidence score:

0.4032
Other information
Title:

Construction of circRNA-based ceRNA network to reveal the role of circRNAs in the progression and prognosis of metastatic clear cell renal cell carcinoma.

Journal: Aging
Published: 2020
PubMed ID: 33223511
Study type:

combined biological and clinical study
Data availability: GSE100186; GSE137836; TCGA-KIRC
Code availability: -