circRNA basic information
circBase ID: hsa_circ_0006156
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr3:171965322-171969331:+
Genomic location(hg38): chr3:172247532-172251541:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

gastric cancer tissues; para-carcinoma normal tissues; cancer tissues; para-carcinoma tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: May be involved in the occurrence and development of gastric cancer; low expression is associated with lymph node metastasis, nerve invasion, tumor recurrence, death, decreased PFS and OS.
Molecular mechanism: -
Biological pathway or process:

metastasis (other); other pathway/process (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Cohort Study; Survival Analysis
Clinical significance:

Related to differentiation degree, lymph node metastasis and prognosis; may serve as a biomarker for prognostic prediction of gastric cancer patients.
Description:

hsa_circ_0006156 is significantly down-regulated in gastric cancer tissues compared with para-carcinoma tissues, and this finding was validated by RT-qPCR. Its reduced expression is associated with lymph node metastasis, nerve invasion, tumor recurrence, death, and poorer survival outcomes, suggesting prognostic biomarker potential.
Confidence score:

0.5202
Other information
Title:

Association between hsa_circ_0006156 expression and incidence of gastric cancer.

Journal: European review for medical and pharmacological sciences
Published: 2020
PubMed ID: 32271420
Study type:

combined biological and clinical study
Data availability: -
Code availability: -